9 Best Supplements for Reducing Inflammation, Say Dietitians

Addressing inflammation has become a popular objective advocated by health influencers and professionals in the healthcare field. Whether dealing with chronic low-grade or acute inflammation, finding effective strategies to combat these effects can yield significant benefits.

While acute inflammation is the body’s immediate response to injury, infection, or tissue damage, chronic low-grade inflammation can arise from various factors, including an unhealthy lifestyle.

Unlike its acute counterpart, chronic low-grade inflammation can have adverse effects, increasing the risk of developing diabetes, cardiovascular disease, and certain cancers.
Consequently, many prioritize reducing chronic low-grade inflammation to safeguard their overall well-being.

In addition to adopting habits like following an anti-inflammatory diet, managing stress, and moderating alcohol consumption, some people turn to supplements to aid them in achieving this goal.

For those eager to alleviate inflammation in their bodies and seeking worthwhile supplement options, continue reading to discover ten recommendations from dietitians known for their potential to reduce inflammation.


According to Anzlovar, incorporating omega-3 fatty acids into your diet has been associated with decreased inflammation and a lower risk of inflammatory conditions like cardiovascular disease.

While it is advisable to obtain omega-3s from food sources like fatty fish, she suggests a supplement if fish consumption is not feasible.

Among the various types of omega-3 fats, EPA and DHA receive significant attention for their anti-inflammatory properties. These beneficial compounds are commonly found in marine sources, particularly oily cold-water fish.

Anzlovar recommends Nordic Naturals Ultimate Omega as a preferred supplement choice due to its combination of EPA and DHA omega-3s and third-party testing for quality assurance.

Another noteworthy anti-inflammatory supplement, according to Melissa Azzaro, RDN, LD, the creator of The Hormone DietitianĀ® LLC, is quercetin.

Quercetin is a compound naturally present in plants such as onions and apples, particularly beneficial for individuals struggling with inflammation related to allergies and asthma. It acts as an antioxidant, anti-inflammatory agent, and immune modulator.

Scientific studies have demonstrated that quercetin can inhibit histamine production, thereby aiding in managing allergy symptoms.


Azzaro highlights resveratrol as a significant compound predominantly found in red grapes and berries. This powerful substance possesses anti-inflammatory, antioxidant, and cardioprotective properties.

Additionally, resveratrol aids in estrogen metabolism and mild uterine contractions. Azzaro specifically suggests resveratrol for individuals experiencing painful period cramps, endometriosis, and fibroids, especially due to its notable anti-inflammatory effects that can bring relief.


Azzaro specifically recommends Boswellia for individuals grappling with inflammation related to inflammatory gut conditions. However, it is important to acknowledge that this supplement may provide anti-inflammatory benefits beyond that scope.

Azzaro elucidates that Boswellia is derived from trees commonly known as frankincense, and scientific research has indicated its anti-inflammatory effects for individuals with inflammatory bowel disease, asthma, and rheumatoid arthritis.


According to Sarah Anzlovar, MS, RDN, LDN, an Intuitive Eating Dietitian for Moms at Sarah Gold Nutrition, LLC, curcumin, the active compound found in turmeric, possesses remarkable anti-inflammatory properties.

Turmeric supplements have shown promise in alleviating symptoms for individuals with inflammatory conditions such as inflammatory bowel disease, osteoarthritis, and rheumatoid arthritis.

An interesting study even demonstrated its effectiveness in reducing joint pain comparable to acetaminophen.

Anzlovar emphasizes the importance of prioritizing inflammation reduction through dietary and lifestyle habits.

However, she acknowledges that turmeric supplements may provide additional support. Her preferred choice is Thorne Curcumin Phytosome, which contains a well-researched form of curcumin known for its potential to reduce joint pain and offer other benefits.

Vitamin D

Vitamin D is commonly associated with its role in promoting bone health, but this essential supplement also possesses the potential to combat chronic low-grade inflammation.

Wan Na Chun, MPH, RD, CPT, a registered dietitian, highlights the multifaceted significance of vitamin D in the body, including its ability to regulate inflammation and support immune function.

She further explains that extensive evidence suggests vitamin D’s diverse effects on immune system function, which can enhance innate immunity and hinder the development of autoimmune conditions.

Omega-3 fatty acid

Anzlovar explains that consuming omega-3 fatty acids has been associated with reduced inflammation and a lower risk of inflammatory diseases, such as cardiovascular disease.

She emphasizes the importance of obtaining omega-3s from food sources like fatty fish but acknowledges that a supplement may be a suitable alternative for those who do not consume fish.

Within the omega-3 category, particular attention is given to DHA and EPA, as they offer notable anti-inflammatory benefits. These essential fatty acids are primarily found in marine sources, particularly oily cold-water fish.

Anzlovar recommends Nordic Naturals Ultimate Omega as her preferred supplement because it provides a balanced combination of both EPA and DHA omega-3s. Additionally, the supplement undergoes third-party testing, ensuring its quality and efficacy.

Tart Cherry

While tart cherry is often recognized as a potential sleep aid, its benefits extend beyond that. This fruit may also play a role in managing inflammation, especially among older adults.

Solaray Ultra Strength Joint InflaShield emerges as a notable supplement option for those seeking relief from inflammation.

It combines the antioxidant properties of tart cherry and resveratrol, targeted joint support from glucosamine and MSM, and the calming effects of IbuActin, all working together to promote everyday well-being and alleviate discomfort.


Ginger root is widely embraced as a flavorful ingredient in numerous culinary creations. However, incorporating ginger into a well-rounded diet can also have potential anti-inflammatory benefits in specific circumstances.

This versatile root contains two notable compounds, gingerol and zingerone, linked to inflammation reduction.

When seeking a reliable ginger supplement, NOW Foods Ginger Root Extract stands out as a trusted option known for its purity and effectiveness, making it suitable for daily consumption.

Green Tea Extract

Green tea is renowned for its anti-inflammatory properties, partly attributed to the presence of a compound called EGCG. Additionally, green tea serves as a source of flavan-3-ols, a plant compound that has demonstrated the ability to diminish oxidative stress.

Life Extension Mega Green Tea Extract offers a concentrated dose of the beneficial compounds naturally found in green tea for individuals seeking a convenient alternative to brewing tea daily.

This supplement presents an excellent choice for those who find it challenging to incorporate a regular tea ritual into their busy schedules.

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